B cell deficiency
MONDO:0002211A broad classification of disorders where circulating numbers of B lymphocytes are decreased or ineffective. Complement components and the production of antibodies may also be deficient.
Also known as: B-cell deficiency, deficiency of humoral immunity, immunoglobulin heavy chain deficiency, immunoglobulin heavy chain deletion
119 clinical trials for this condition and its sub-types, 5 tagged with B cell deficiency itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of B cell deficiency
-
Agammaglobulinemia 16 trials · 52 incl. sub-types
10 sub-types
- Syndromic agammaglobulinemia 7 trials · 37 incl. sub-types Sub-types →
- Activated PI3K-delta syndrome 5 trials · 6 incl. sub-types Sub-types →
- Isolated agammaglobulinemia 0 trials · 4 incl. sub-types Sub-types →
- Good syndrome 0 trials
- Agammaglobulinemia 10, autosomal dominant 0 trials
- Agammaglobulinemia 8b, autosomal recessive 0 trials
- Agammaglobulinemia 9, autosomal recessive 0 trials
- Agammaglobulinemia, autosomal recessive, due to BOB1 deficiency 0 trials
- Congenital agammaglobulinemia 0 trials Sub-types →
- Immunodeficiency 61 0 trials
-
Hyperimmunoglobulin syndrome 0 trials · 34 incl. sub-types
2 sub-types
- Hyper-IgE syndrome 5 trials · 26 incl. sub-types Sub-types →
- Hyper-IgM syndrome 8 trials · 9 incl. sub-types Sub-types →
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Selective immunoglobulin deficiency disease 1 trial · 4 incl. sub-types
2 sub-types
- Dysgammaglobulinemia 1 trial · 4 incl. sub-types Sub-types →
- Selective IgD deficiency disease 0 trials
-
Immunoglobulin beta deficiency 0 trials
Most studied deeper sub-types
Common variable immunodeficiency
(29)
Netherton syndrome
(16)
Combined immunodeficiency due to DOCK8 deficiency
(6)
Immunodeficiency 14
(6)
Bruton-type agammaglobulinemia
(4)
Hyper-IgE recurrent infection syndrome 1, autosomal dominant
(3)
Hyper-IgM syndrome type 1
(3)
Selective IgA deficiency disease
(2)
Selective IgG immunodeficiency
(2)
Selective IgG subclass deficiency
(2)
Selective IgM deficiency
(2)
Autosomal agammaglobulinemia
(1)
Hyper-IgM syndrome type 2
(1)
Hyper-IgM syndrome type 3
(1)
Hyper-IgM syndrome type 5
(1)
Immunodeficiency, common variable, 12
(1)
Pancytopenia due to IKZF1 mutations
(1)
Agammaglobulinemia 2, autosomal recessive
(0)
Agammaglobulinemia 3, autosomal recessive
(0)
Agammaglobulinemia 4, autosomal recessive
(0)