Autosomal dominant Parkinson disease 4
MONDO:0011562A late onset Parkinson disease that has material basis in heterozygous triplication of the alpha-synuclein gene (SNCA) on chromosome 4q22.
Also known as: autosomal dominant Parkinson disease 4, autosomal dominant Parkinson disease type 4, PARK4, Parkinson disease 4, autosomal dominant, Parkinson disease 4, autosomal dominant Lewy body, autosomal dominant Parkinson's disease 4
148 clinical trials for this condition and its sub-types, 136 tagged with Autosomal dominant Parkinson disease 4 itself.
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Can a common diabetes drug ease Parkinson's symptoms?
Disease control Not yet recruitingThis trial tests whether adding metformin, a common diabetes drug, to standard Parkinson's treatment improves motor symptoms and reduces levels of harmful proteins and oxidative stress markers in the blood. Researchers will compare Parkinson's patients aged 50 to 70 who receive m…
Phase 4 • Sponsor: Jinnah Medical & Dental College • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Can adding immunotherapy to standard care beat a tough head and neck cancer?
Disease control Not yet recruitingThis phase 2 trial is testing whether adding an immunotherapy drug called tislelizumab to the standard treatment of chemotherapy and radiation can improve outcomes for people with advanced head and neck cancer that is not linked to HPV and cannot be removed with surgery. Particip…
Phase 2 • Sponsor: Fudan University • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
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Could stem cells ease Parkinson's symptoms? new trial launches
Disease control Not yet recruitingThis study tests two types of stem cell treatments for people with Parkinsonism, a condition that causes movement and non-movement problems. The goal is to see if these treatments are safe and can improve symptoms like tremors, stiffness, and mood changes. About 120 adults aged 4…
Phase 2 • Sponsor: Biocells Medical • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Could zapping the spine steady blood pressure in Parkinson's?
Disease control Not yet recruitingThis study tests whether spinal cord stimulation can help people with Parkinson's disease who experience sudden drops in blood pressure when standing up. Forty participants will receive either an implanted stimulator or a non-invasive version. The goal is to see if the treatment …
Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC