Autosomal dominant cerebellar ataxia type I
MONDO:0019792Autosomal dominant cerebellar ataxia (ADCA) type I is a group of spinocerebellar ataxias (SCAs) characterized by ataxia with other neurological signs, including oculomotor disturbances, cognitive deficits, pyramidal and extrapyramidal dysfunction, bulbar, spinal and peripheral nervous system involvement.
Also known as: ADCA1, ADCAI, autosomal dominant cerebellar ataxia type 1, cerebellar plus syndrome
35 clinical trials for this condition and its sub-types, 0 tagged with Autosomal dominant cerebellar ataxia type I itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Autosomal dominant cerebellar ataxia type I
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Machado-Joseph disease 11 trials
4 sub-types
- Machado-Joseph disease type 3 2 trials
- Machado-Joseph disease type 1 0 trials
- Machado-Joseph disease type 2 0 trials
- Machado-Joseph disease type 4 0 trials
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Spinocerebellar ataxia type 1 10 trials
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Spinocerebellar ataxia type 2 10 trials
1 sub-type
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Spinocerebellar ataxia type 8 4 trials
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Spinocerebellar ataxia type 27 2 trials
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Spinocerebellar ataxia type 23 1 trial
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Spinocerebellar ataxia type 29 1 trial
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Spinocerebellar ataxia 46 0 trials
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Spinocerebellar ataxia type 12 0 trials
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Spinocerebellar ataxia type 13 0 trials
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Spinocerebellar ataxia type 14 0 trials
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Spinocerebellar ataxia type 15/16 0 trials
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Spinocerebellar ataxia type 17 0 trials
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Spinocerebellar ataxia type 18 0 trials
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Spinocerebellar ataxia type 19/22 0 trials
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Spinocerebellar ataxia type 20 0 trials
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Spinocerebellar ataxia type 21 0 trials
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Spinocerebellar ataxia type 25 0 trials
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Spinocerebellar ataxia type 28 0 trials
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Spinocerebellar ataxia type 32 0 trials
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Spinocerebellar ataxia type 34 0 trials
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Spinocerebellar ataxia type 35 0 trials
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Spinocerebellar ataxia type 36 0 trials
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Spinocerebellar ataxia type 37 0 trials
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Spinocerebellar ataxia type 4 0 trials
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Spinocerebellar ataxia type 40 0 trials
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Can targeted brain zaps ease movement problems in a rare ataxia?
Disease control Not yet recruitingThis trial tests a non-invasive brain stimulation technique called transcranial temporal interference stimulation (tTIS) in people with spinocerebellar ataxia type 3, a genetic condition that affects coordination and balance. The stimulation targets a deep brain region involved i…
Sponsor: First Affiliated Hospital of Fujian Medical University • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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Can brain stimulation tame ataxia?
Disease control Not yet recruitingThis trial tests whether deep brain stimulation (DBS) targeting the cerebellum is safe and feasible for people with spinocerebellar ataxia types 1 and 3, a group of inherited disorders that cause progressive problems with movement and coordination. The study will enroll 12 adults…
Sponsor: Gordon H. Baltuch • Aim: Disease control
Last updated Aug 09, 2026 00:00 UTC
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Could stem cells help people with spinocerebellar ataxia? new trial aims to find out
Disease control Not yet recruitingThis Phase 2 trial tests whether umbilical cord stem cells can safely improve movement and coordination in people with spinocerebellar ataxia (types 1, 2, 3, and 6). Forty-five participants will receive the cells through an IV and a spinal injection. The main goal is to see if sy…
Phase 2 • Sponsor: Sclnow Biotechnology Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Can intense walking training help brain injury patients walk better?
Symptom relief Not yet recruitingThis study looks at whether high-intensity walking training can help people with cerebellar damage (a part of the brain that controls balance and coordination) improve their walking ability. Twenty participants will either do intense walking exercises or standard training. The go…
Sponsor: Indiana University • Aim: Symptom relief
Last updated Jun 27, 2026 13:01 UTC
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AI vs. experts: can a computer judge speech as well as a human?
Knowledge-focused Not yet recruitingThis study will compare how well an AI program (Blings) measures speech clarity in 40 adults with speech disorders from stroke or other neurological conditions. Two speech therapists will also rate the same speech samples. The goal is to see if the AI can reliably replace or assi…
Sponsor: Pusan National University Yangsan Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC