Autoimmune enteropathy

MONDO:0019787

Severe-immune mediated enteropathy describes a variety of intestinal disorders that can range from a serious, early-onset systemic disease (IPEX) to a mild isolated gastrointestinal disease. In children it manifests with severe diarrhea and dehydration in the presence of characteristic antibodies (anti-enterocyte and anti-goblet cell) and in adults with chronic diarrhea, malabsorption and weight loss.

Also known as: immune-mediated protracted diarrhea of infancy, immune-mediated protracted diarrhoea of infancy, severe immune-mediated enteropathy

47 clinical trials for this condition and its sub-types, 2 tagged with Autoimmune enteropathy itself.

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Where it sits in the disease tree

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Part of

↑ Autoimmune disorder of gastrointestinal tract (936) ↑ Malabsorption syndrome (118)

Sub-types of Autoimmune enteropathy

Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome 10 trials
Autoimmune enteropathy and endocrinopathy - susceptibility to chronic infections syndrome 0 trials
Autoimmune enteropathy type 3 0 trials
Primary autoimmune enteropathy 0 trials

Including sub-types (47) Tagged with Autoimmune enteropathy (2)

Trials to join now! 1 Completed 1

Scientists dig into why the immune system turns on the gut

Knowledge-focused Recruiting now

This study is looking at why the immune system attacks the gut in people with celiac disease and other immune-related gut disorders. Researchers will collect blood and tissue samples from 200 adults to study immune cells and genes. The goal is to better understand what goes wrong…

Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused

Last updated Jun 26, 2026 18:35 UTC

Autoimmune enteropathy

Where it sits in the disease tree

Scientists dig into why the immune system turns on the gut