Autism spectrum disorder 1
MONDO:0100610The mildest form of autism spectrum disorder, characterized by difficulties with social communication and restricted, repetitive behaviors, requiring minimal support for daily functioning.
Also known as: Asperger syndrome, autism spectrum disorder without disorder of intellectual development and with mild or no impairment of functional language
18 clinical trials for this condition and its sub-types, 15 tagged with Autism spectrum disorder 1 itself.
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Virtual coaching for parents may boost social skills in kids with autism
Symptom relief CompletedThis study compares online parent coaching to in-person coaching for improving social communication in toddlers with autism or social communication delays. About 188 children aged 18-33 months will take part. Parents learn techniques to engage their child during play, aiming to i…
Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc. • Aim: Symptom relief
Last updated Aug 08, 2026 00:03 UTC
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New therapy helps autistic teens tame anger without medication
Symptom relief CompletedThis study tested a new behavior therapy for teens with autism who struggle with irritability and aggression. The therapy teaches emotion regulation and coping skills for the challenges of growing up. 65 adolescents participated, and researchers measured changes in aggressive beh…
Sponsor: Yale University • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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New parent support programme shows promise for families of children with complex needs
Symptom relief CompletedThis pilot study tested a community-based group programme called 'Encompass' for parents of children under 5 with complex neurodisability. Fifteen parents in East London attended ten group sessions over six months. The study aimed to see if the programme was feasible and acceptab…
Sponsor: City, University of London • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Talking therapy shows promise for autism Self-Harm
Symptom relief CompletedThis study tested whether a 5-month program of dialectical behavior therapy (DBT) can help adults with autism who struggle with self-harm or suicidal thoughts. Researchers enrolled 92 adults with autism and no intellectual disability. The goal was to see if DBT reduces emotional …
Sponsor: University Hospital, Strasbourg, France • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Could a common ADHD drug ease hyperactivity in kids with autism?
Symptom relief CompletedThis study tested the drug atomoxetine in 60 children with autism who also had significant hyperactivity, inattention, or impulsivity. Over 8 weeks, researchers measured changes in ADHD symptoms using a standard rating scale. The goal was to see if atomoxetine could safely reduce…
Phase 3 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Massive brain study seeks clues to Autism's mysteries
Knowledge-focused CompletedThis study aimed to understand the brain and genetics behind autism spectrum disorders (ASD). Researchers compared brain scans, thinking tests, and DNA from 678 people with ASD, healthy volunteers, and their parents. The goal was to find links between brain activity, behavior, an…
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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NIH study aims to sharpen research skills by evaluating kids with genetic disorders
Knowledge-focused CompletedThis completed study at the NIH enrolled 96 children with known or suspected genetic disorders, including autism and Fragile X syndrome. The main goal was to give clinic staff hands-on experience and explore new research ideas. Participants received medical exams, lab tests, and …
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Sep 02, 2026 00:00 UTC
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Brain-Body signals could reveal hidden patterns in autism, ADHD, and Alzheimer's
Knowledge-focused CompletedThis completed study at Rutgers University looked at how the brain and body communicate in 30 people with conditions like autism, ADHD, Alzheimer's, and Parkinson's. Participants performed natural movements like walking and pointing while their brain, heart, and motion signals we…
Sponsor: Rutgers University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Autism study links poor posture and hand function to feeding problems in children
Knowledge-focused CompletedThis study looked at 40 children with autism and 40 healthy children, ages 5 to 10, to see how posture, hand function, and sensory processing affect nutrition. Researchers measured head posture, balance, hand strength, and feeding behaviors. They found that children with autism h…
Sponsor: Bezmialem Vakif University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC