Atypical coarctation of aorta
MONDO:0015446Middle aortic coarctation is a rare vascular anomaly characterized by the segmental narrowing of the abdominal and/or distal descending thoracic aorta with varying involvement of the visceral and renal arteries that commonly presents in children and young adults with early onset and refractory hypertension, abdominal angina, lower-limb claudication and that can lead to life-threatening complications associated with severe hypertension (i.e. myocardial infarction, heart failure, aortic rupture, renal insufficiency and intracranial hemorrhage). It may be due to various congenital or acquired causes, but it is most often secondary to an acquired inflammatory disease (i.e. Takayasu arteritis or giant cell arteritis).
Also known as: Midaortic syndrome, coarctation of the abdominal aorta, mid-aortic dysplastic syndrome, mid-aortic syndrome, middle aortic syndrome
7 clinical trials for this condition and its sub-types, 0 tagged with Atypical coarctation of aorta itself.
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Registry tracks graft performance in 1,200 artery patients
Disease control Recruiting nowThis study follows 1,200 people who received special fabric tubes (grafts) to repair or replace damaged arteries in the neck, belly, or legs. Researchers want to see how well the grafts work over time and how often problems like blockages or infections happen. It is an observatio…
Sponsor: Intervascular • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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New device aims to make aortic surgery safer
Disease control Recruiting nowThis study tests a new device called Rapidlink, used during open surgery to repair or replace blood vessels in the chest. It involves 150 adults already scheduled for aortic surgery. The goal is to see if the device reduces major complications like stroke or death. Participants w…
Sponsor: Vascutek Ltd. • Aim: Disease control
Last updated Jul 29, 2026 00:00 UTC
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Shockwave therapy opens hardened arteries for Life-Saving aortic repair
Disease control Recruiting nowThis study tests a special balloon that uses shockwaves to crack calcium buildup in the iliac arteries, making it possible to deliver large aortic stents. About 40 adults with severe aortic disease and hardened arteries will be enrolled. The goal is to see if this approach is saf…
Sponsor: EndoCore Lab s.r.l. • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Aortic disease study seeks to uncover hidden toll on work and Well-Being
Knowledge-focused Recruiting nowThis study tracks 300 adults with aortic disease to measure how their condition impacts quality of life, fatigue, mental health, and ability to work. Researchers will use questionnaires over 12 months to gather data. The goal is to better understand these challenges and help desi…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Massive heart biobank aims to unlock secrets of aortic disease
Knowledge-focused Recruiting nowThis study is creating a large biobank of blood, DNA, plasma, and tissue samples from 15,000 people with and without heart and aortic diseases. Researchers will use this information to better understand conditions like aortic aneurysm, heart failure, and bicuspid aortic valve. Th…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC