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Atopic IgE-mediated allergic disorder
MONDO:0005202A genetic predisposition to form IgE antibodies in response to exposure to allergens and therefore, for the development of immediate (type I) hypersensitivity and atopic conditions, such as allergic rhinitis; bronchial asthma, atopic dermatitis, and food allergy. Mutations of specific alleles on the long arm of chromosome 5 have been associated with higher levels of IL-4 and IgE and are known as IL-4 promoter polymorphisms.
Also known as: Atopic allergy, atopic state, atopy
20 clinical trials for this condition and its sub-types, 13 tagged with Atopic IgE-mediated allergic disorder itself.
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New eczema drug shows promise in Mid-Stage trial
Disease control Recruiting nowThis study tests a new medication called camoteskimab for adults with moderate-to-severe atopic dermatitis (eczema). About 280 participants will receive either the drug or a placebo to see if it reduces skin redness, thickness, and itching over 24 weeks. The goal is to find a saf…
Phase 2 • Sponsor: Apollo Therapeutics Ltd • Aim: Disease control
Last updated Aug 30, 2026 00:00 UTC
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New antibody aims to neutralize allergies by clearing IgE
Disease control Recruiting nowThis early-stage trial tests an experimental antibody drug called LCA-0061, designed to target and remove immunoglobulin E (IgE), a key driver of allergic reactions. The study first evaluates safety and tolerability in healthy people with elevated IgE levels, then in people with …
Phase 1 • Sponsor: Lycia Therapeutics, Inc. • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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EATING YOUR WAY TO CLEARER SKIN? NEW STUDY TESTS DIET FOR ECZEMA
Symptom relief Recruiting nowThis study tests whether a diet low in saturated fats and rich in whole grains, fruits, and vegetables can reduce the severity of atopic dermatitis (eczema) in young adults. Researchers will track changes in skin symptoms and barrier function over two months. The goal is to see i…
Sponsor: National University of Singapore • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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20,000 volunteers needed to decode immune disease genetics
Knowledge-focused Recruiting nowThis study will analyze DNA from up to 20,000 people, including those with immune disorders and their relatives, to find genetic variants linked to conditions like atopy, autoimmunity, and primary immunodeficiency. Researchers will also study how best to return genetic results to…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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10,000 volunteers needed to unlock allergy mysteries
Knowledge-focused Recruiting nowThis study aims to collect blood, nasal fluid, skin cells, urine, and medical data from 10,000 people aged 3 to 100 with allergies, asthma, eczema, or sinus issues. Participants will have up to 3 years of follow-up visits and questionnaires. The goal is to create a large reposito…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Mali allergy study seeks clues in gut and skin germs
Knowledge-focused Recruiting nowThis study examines how germs living on and in the body, along with environmental factors like pollution, may influence allergic diseases such as asthma and eczema in people living in Mali. Researchers will collect samples and health information from 288 participants, both with a…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC