Aspirin-induced respiratory disease
MONDO:0850287An intrinsic asthma that is characertized by severe and prolonged airway obstruction after the ingestion of aspirin or other non-steroidal anti-inflammatory drugs.
6 clinical trials for this condition and its sub-types, 5 tagged with Aspirin-induced respiratory disease itself.
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Fish oil shows promise for Tough-to-Treat asthma
Disease control CompletedThis study tested whether taking high-dose fish oil (n-3 PUFA) for 6 months can improve asthma control in adults with a specific type of asthma called N-ERD, which is triggered by aspirin or NSAIDs. The 18 participants had poorly controlled asthma despite standard treatment. The …
Phase 3 • Sponsor: Norfolk and Norwich University Hospitals NHS Foundation Trust • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New hope for asthma and polyp sufferers? mepolizumab under the microscope
Disease control CompletedThis study looked at whether the drug mepolizumab can improve symptoms in people with a specific combination of asthma, nasal polyps, and sensitivity to aspirin or similar painkillers. 95 adults received either mepolizumab or a placebo injection every month for 16 weeks. Research…
Phase 4 • Sponsor: Helsinki University Central Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New asthma drug may change how patients react to aspirin
Knowledge-focused CompletedThis study looked at how dupilumab, a drug for asthma and nasal polyps, affects reactions to aspirin in people with AERD (a severe form of asthma with sinus issues). 16 adults who were already taking dupilumab for at least 12 weeks took part. Researchers measured breathing, nasal…
Phase 2 • Sponsor: Scripps Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Scientists probe immune Molecule's role in stuffy nose disease
Knowledge-focused CompletedThis study looked at how a molecule called IL-5 affects different cells in the sinuses of people with nasal polyps and a related condition called aspirin-exacerbated respiratory disease. Researchers analyzed tissue samples from 30 participants to understand how IL-5 contributes t…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC