Apnea of prematurity
MONDO:0020567Apnea of prematurity is a developmental disorder affecting premature infants, likely secondary to an immaturity of respiratory control resulting in idiopathic pauses in breathing often associated with reduced heart rate and arterial blood oxygen levels. It may be exacerbated by concurrent neonatal diseases.
20 clinical trials for this condition and its sub-types, 20 tagged with Apnea of prematurity itself.
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A pinprick of blood could Fine-Tune caffeine dosing for preemies
Diagnosis Not yet recruitingThis study tests whether a small device called Mitra can collect a tiny drop of blood from premature babies to measure caffeine levels. Caffeine is commonly given to preterm infants to prevent apnea, but finding the right dose is tricky—too little may cause breathing pauses, and …
Sponsor: University Hospital, Limoges • Aim: Diagnosis
Last updated Aug 23, 2026 00:00 UTC
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Smartphone app could stop breathing pauses in preterm infants
Symptom relief Not yet recruitingThis study tests a smartphone app that predicts when preterm babies will have pauses in breathing (apnea) and slow heart rate (bradycardia). The app then triggers gentle stimulation to prevent these episodes. The study will include 25 preterm infants born before 32 weeks who have…
Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Jul 09, 2026 00:00 UTC
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Could a muscle relaxant make newborn intubation safer?
Symptom relief Not yet recruitingThis study tests whether adding a muscle relaxant (rocuronium) to standard painkiller (fentanyl) helps doctors place breathing tubes in newborns on the first try, without causing dangerous drops in oxygen or heart rate. About 102 premature or sick babies in a Brazilian NICU will …
Phase 4 • Sponsor: UEA - Universidade Do Estado Do Amazonas • Aim: Symptom relief
Last updated Jul 03, 2026 00:00 UTC
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Caffeine could steady preemie hearts, tiny study hopes
Symptom relief Not yet recruitingThis study will check if caffeine, already used to treat breathing pauses in premature babies, also helps keep their heart rate and blood pressure steady. Researchers will monitor 40 preterm infants in the NICU before and after caffeine treatment. The goal is to see if caffeine i…
Sponsor: Assiut University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC