Aortitis

This study follows 1,200 people who received special fabric tubes (grafts) to repair or replace damaged arteries in the neck, belly, or legs. Researchers want to see how well the grafts work over time and how often problems like blockages or infections happen. It is an observatio…

This study tests a new device called Rapidlink, used during open surgery to repair or replace blood vessels in the chest. It involves 150 adults already scheduled for aortic surgery. The goal is to see if the device reduces major complications like stroke or death. Participants w…

This study tests a special balloon that uses shockwaves to crack calcium buildup in the iliac arteries, making it possible to deliver large aortic stents. About 40 adults with severe aortic disease and hardened arteries will be enrolled. The goal is to see if this approach is saf…

This study tracks 300 adults with aortic disease to measure how their condition impacts quality of life, fatigue, mental health, and ability to work. Researchers will use questionnaires over 12 months to gather data. The goal is to better understand these challenges and help desi…

This study is creating a large biobank of blood, DNA, plasma, and tissue samples from 15,000 people with and without heart and aortic diseases. Researchers will use this information to better understand conditions like aortic aneurysm, heart failure, and bicuspid aortic valve. Th…

This study collects tissue samples from 1,000 people with various forms of vasculitis, a group of rare inflammatory blood vessel diseases. Researchers will analyze the samples alongside clinical data to identify genes that increase risk and to spark new ideas for diagnosis and tr…

This study is following 670 adults with vasculitis, a rare blood vessel disease, for up to 5 years. Researchers will collect medical data and blood samples to see how the disease starts, how it is treated, and what long-term problems may arise. No new treatments are being tested—…