Aortic valve insufficiency
MONDO:0005648Dysfunction of the aortic valve characterized by incomplete valve closure.
Also known as: aortic insufficiency, rheumatic aortic insufficiency, rheumatic aortic regurgitation
110 clinical trials for this condition and its sub-types, 56 tagged with Aortic valve insufficiency itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Aortic valve insufficiency
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Can a less invasive valve replacement tame a failing aortic valve?
Disease control Stopped earlyThis study is a patient registry that collects information on people with severe aortic stenosis or aortic regurgitation who are treated with the Trilogy heart valve system, a device implanted via a catheter (TAVI) to replace the aortic valve without open-heart surgery. The goal …
Sponsor: JenaValve Technology, Inc. • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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Massive german study compares new and old heart valve procedures
Knowledge-focused Stopped earlyThis study was a large registry that planned to follow 180,000 patients in Germany with aortic valve problems (leaky or narrowed valves). The goal was to compare newer, less invasive treatments like TAVI with standard open-heart surgery to see which works best and for whom. Resea…
Sponsor: German Aortic Valve Registry • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC