Aortic valve disorder
MONDO:0003803A disease involving the aortic valve.
Also known as: aortic valve disease, aortic valve disease or disorder, aortic valve disorder, disease of aortic valve, disease or disorder of aortic valve, disorder of aortic valve
427 clinical trials for this condition and its sub-types, 77 tagged with Aortic valve disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Aortic valve disorder
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Aortic valve stenosis 319 trials · 322 incl. sub-types
4 sub-types
- Supravalvular aortic stenosis 3 trials
- Childhood aortic valve stenosis 0 trials
- Congenital aortic valve stenosis 0 trials Sub-types →
- Subvalvular aortic stenosis 0 trials Sub-types →
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Aortic valve insufficiency 56 trials
1 sub-type
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Familial bicuspid aortic valve 6 trials · 21 incl. sub-types
3 sub-types
- Aortic valve disease 1 16 trials
- Aortic valve disease 2 12 trials
- Aortic valve disease 3 0 trials
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Aortic valve calcification 14 trials
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Aortic valve prolapse 0 trials
Most studied deeper sub-types
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Can a less invasive valve replacement tame a failing aortic valve?
Disease control Stopped earlyThis study is a patient registry that collects information on people with severe aortic stenosis or aortic regurgitation who are treated with the Trilogy heart valve system, a device implanted via a catheter (TAVI) to replace the aortic valve without open-heart surgery. The goal …
Sponsor: JenaValve Technology, Inc. • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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Heart surgery drug may keep blood pressure steady
Symptom relief Stopped earlyThis study tested whether a drug called Polaramine can prevent dangerous drops in blood pressure when patients come off a heart-lung machine during aortic valve replacement. 18 adults took part. The goal was to see if the drug helps the body keep a stable blood pressure after sur…
Phase 3 • Sponsor: University Hospital, Bordeaux • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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Heart-Lung Machine's gut impact studied in small trial
Knowledge-focused Stopped earlyThis study aimed to see if the heart-lung machine used during heart surgery changes blood flow in the gut. Researchers checked blood flow under the tongue as a way to measure gut health. The study was stopped early and included only 21 adults having aortic valve replacement. It w…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC