Aortic disorder
MONDO:0005561Pathology involving the thoracic, thoracoabdominal, or abdominal aorta (including aneurysms). (ACC)
Also known as: aorta disease, aorta disease or disorder, disease of aorta, disease or disorder of aorta, disorder of aorta
645 clinical trials for this condition and its sub-types, 45 tagged with Aortic disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Aortic disorder
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Aortic valve disorder 77 trials · 398 incl. sub-types
5 sub-types
- Aortic valve stenosis 319 trials · 322 incl. sub-types Sub-types →
- Aortic valve insufficiency 56 trials Sub-types →
- Familial bicuspid aortic valve 6 trials · 21 incl. sub-types Sub-types →
- Aortic valve calcification 14 trials
- Aortic valve prolapse 0 trials
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Aortic aneurysm 104 trials · 208 incl. sub-types
2 sub-types
- Abdominal aortic aneurysm 113 trials Sub-types →
- Thoracic aortic aneurysm 75 trials
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Aorta coarctation 13 trials
2 sub-types
- Atypical coarctation of aorta 0 trials
- Autosomal dominant coarctation of aorta 0 trials
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Leriche syndrome 8 trials
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Renal artery disease 3 trials · 7 incl. sub-types
3 sub-types
- Renal artery atheroma 4 trials
- Renal artery obstruction 3 trials
- Nephrosclerosis 0 trials
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Aortic atherosclerosis 1 trial · 5 incl. sub-types
1 sub-type
- Renal artery atheroma 4 trials
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Superior mesenteric artery syndrome 2 trials
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Tricuspid valve stenosis 2 trials
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Aortitis 1 trial
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Aneurysm of sinus of Valsalva 0 trials
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Aorta atresia 0 trials
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Aortic malignant tumor 0 trials
1 sub-type
- Aorta angiosarcoma 0 trials
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Neoplasm of aortic body 0 trials
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Subaortic stenosis, membranous 0 trials
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Tricuspid valve prolapse 0 trials
Most studied deeper sub-types
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New stent aims to fix aortic aneurysms without open surgery
Disease control OngoingThis study is testing a new stent device called the GORE® TAG® Thoracic Branch Endoprosthesis to treat aneurysms or lesions in the aortic arch and upper part of the main artery from the heart. About 250 participants will receive the device to see if it is safe and effective. The …
Sponsor: W.L.Gore & Associates • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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New stent graft could fix Life-Threatening aorta tears without open surgery
Disease control By invitation onlyThis study tests a special tube called a stent graft to repair damage in the upper part of the main artery from the heart (the ascending aorta). It is for people with bulges (aneurysms), tears (dissections), or other lesions that usually need open-heart surgery. The goal is to se…
Sponsor: W.L.Gore & Associates • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New Blood-Clot monitor could cut transfusions in heart surgery
Disease control OngoingThis study tests whether a bedside device called Quantra can help doctors decide when to give blood transfusions during complex heart surgery. The device measures how well a patient's blood clots in real time. Researchers hope this will reduce the number of blood products (like r…
Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New stent registry aims to improve aortic dissection outcomes
Disease control OngoingThis study is a registry that collects information on the AMDS stent, a device used to treat a life-threatening tear in the aorta (the main artery). The registry includes 301 adults aged 18-80 with acute DeBakey type I aortic dissection or intramural hematoma. The goal is to see …
Sponsor: JOTEC GmbH • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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New stent aims to save lives from aortic tears
Disease control OngoingThis study tests a new stent (Talos) for treating a life-threatening tear in the aorta, the body's main artery. The stent has special features to improve blood flow and reduce complications. 320 adults with aortic dissection will be followed for 2 years to see if the stent helps …
Sponsor: Qingyou Meng • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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AI plus ultrasound could catch heart and lung decline before it turns critical
Diagnosis By invitation onlyResearchers are testing whether artificial intelligence can combine ultrasound images with routine health data to track changes in a person's physiology over time. The study enrolls adults with heart, lung, kidney, or blood vessel conditions, as well as healthy volunteers. The go…
Sponsor: Truway Health, Inc. • Aim: Diagnosis
Last updated Sep 12, 2026 00:00 UTC
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Heart valve mystery: scientists hunt for genetic clues in 1,000 patients
Knowledge-focused OngoingThis study collects tissue samples from 1,000 people having heart valve surgery to find genetic causes of calcific aortic valve disease. Researchers will compare normal and diseased tissue to understand why the disease develops. Participants must be at least 20 years old and have…
Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Massive study aims to improve survival after aortic tear surgery
Knowledge-focused By invitation onlyThis study collects data from 1,200 patients undergoing surgery for aortic dissection, a life-threatening tear in the heart's main artery. Researchers will track death rates, strokes, and other complications to identify the safest surgical strategies. The goal is to improve outco…
Sponsor: Centre Cardiologique du Nord • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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AI could help heart surgery patients get the right Anti-Inflammatory drug
Knowledge-focused OngoingThis study is looking at whether an artificial intelligence tool can help doctors decide which heart surgery patients might benefit from a drug called ulinastatin. Ulinastatin is used to reduce inflammation after surgery, but it doesn't work for everyone. Researchers will analyze…
Sponsor: Beijing Anzhen Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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New study aims to personalize monitoring of aortic aneurysms
Knowledge-focused By invitation onlyThis study is collecting data from 400 people with abdominal aortic aneurysms to improve how doctors predict aneurysm growth. The goal is to create more personalized monitoring plans. Participants will have regular check-ups and imaging tests to track changes over time.
Sponsor: Karolinska University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Scientists hunt for hidden genes behind aortic aneurysms
Knowledge-focused OngoingThis study aims to uncover the genetic roots of aortic aneurysms and valve disease by analyzing tissue and blood samples from 3,000 participants. Researchers will look for new disease-causing genes and factors that affect disease severity. The goal is to build a biorepository to …
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC