Aorta coarctation
MONDO:0007345Congenital narrowing of a segment of the aorta. Signs and symptoms include hypertension, muscle weakness, shortness of breath, headaches and leg cramps.
Also known as: aortic coarctation, coarctation of aorta, coarctation of the aorta
20 clinical trials for this condition and its sub-types, 13 tagged with Aorta coarctation itself.
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Sub-types of Aorta coarctation
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Atypical coarctation of aorta 0 trials
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Can a blood pressure drug reverse heart scarring after aortic repair?
Disease control Recruiting nowThis trial tests whether losartan, a common blood pressure medication, can reduce scarring in the heart's main pumping chamber and improve exercise capacity in adults who had surgery to repair coarctation of the aorta. Participants will take losartan, amlodipine, or a placebo dai…
Phase 3 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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New trial aims to halve deaths in newborns with severe heart disease
Disease control Recruiting nowThis study compares performing heart surgery on newborns with complex congenital heart disease either before or after 7 days of age. Researchers will track which timing leads to fewer deaths and better recovery. The trial involves 738 babies across multiple hospitals in China.
Sponsor: Central China Fuwai Hospital of Zhengzhou University • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Dissolving iron stent offers hope for aortic narrowing
Disease control Recruiting nowThis study tests a new type of stent made from iron that slowly dissolves in the body. It is designed to treat coarctation of the aorta, a condition where the main artery from the heart is narrowed. The study will enroll 10 people aged 1 to 60 to see if the stent is safe and effe…
Sponsor: Shubo Song • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Mini stent offers hope for babies with blocked heart arteries
Disease control Recruiting nowThis study is for babies, infants, and small children who have narrowed arteries in or near the heart. Doctors will use a special tiny stent to open the blockage and improve blood flow. The goal is to see how well the stent works and to track any side effects in everyday medical …
Sponsor: Renata Medical • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Heart defect mystery: can remote monitoring predict dangerous rhythms?
Knowledge-focused Recruiting nowThis study aims to understand why people with tetralogy of Fallot and other congenital heart diseases experience shortness of breath, palpitations, and changes in heart structure. Researchers will use remote heart rhythm monitors and imaging to track 300 participants over two yea…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC