Anterior segment dysgenesis
MONDO:0019503A spectrum of developmental anomalies that affect the development of the anterior segment of the eyeball resulting from abnormalities of neural crest migration and differentiation during embryologic development (Axenfeld-Rieger syndrome, Peters anomaly, posterior keratoconus, and iridoschisis).
Also known as: ASGD, ASMD, ASOD, anterior segment mesenchymal dysgenesis, anterior segment ocular dysgenesis, familial ocular anterior segment mesenchymal dysgenesis
21 clinical trials for this condition and its sub-types, 2 tagged with Anterior segment dysgenesis itself.
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Sub-types of Anterior segment dysgenesis
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Congenital primary aphakia 17 trials
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Iridogoniodysgenesis 0 trials · 2 incl. sub-types
7 sub-types
- FOXC1-related anterior segment dysgenesis 0 trials · 1 incl. sub-types Sub-types →
- Congenital microcoria 1 trial
- Rieger anomaly 0 trials Sub-types →
- Aniridia-cerebellar ataxia-intellectual disability syndrome 0 trials
- Bilateral acute depigmentation of the iris 0 trials
- Chromosome 6pter-p24 deletion syndrome 0 trials
- Congenital ectropion uveae 0 trials
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Peters anomaly 1 trial
2 sub-types
- Peters anomaly-cataract syndrome 0 trials
- Von Hippel anomaly 0 trials
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Anterior segment dysgenesis 1 1 trial
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Anterior segment dysgenesis 6 1 trial
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Anterior segment dysgenesis 7 0 trials
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Anterior segment dysgenesis 8 0 trials
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Isolated iridoschisis 0 trials
Most studied deeper sub-types
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New lens implant aims to sharpen sight after cataracts
Disease control Recruiting nowThis study is testing a new type of artificial lens, called the Clareon TruPlus, for people having cataract surgery. The lens is placed inside the eye to replace the cloudy natural lens and help restore clear vision. About 122 adults with cataracts and astigmatism will receive th…
Sponsor: Alcon Research • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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New lens implants promise clearer vision for complex cataract cases
Disease control Recruiting nowThis study tests special lens implants that correct both cataracts and presbyopia (age-related blurry near vision) in patients with additional eye structure issues like lens dislocation or inflammation. About 320 adults will receive these lenses during cataract surgery, with doct…
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New lens aims to sharpen sight at all distances
Symptom relief Recruiting nowThis study tests a new type of artificial lens (LuxBoost) for people having cataract surgery. The goal is to see if it improves vision at far, middle, and close distances compared to a standard lens. About 58 adults aged 50 and older with cataracts in both eyes will take part.
Sponsor: Cutting Edge SAS • Aim: Symptom relief
Last updated Aug 20, 2026 00:00 UTC
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800 kids with rare eye conditions to be tracked for 10 years
Knowledge-focused Recruiting nowThis study follows 800 children born with eye malformations like microphthalmia, anophthalmia, aniridia, or anterior segment defects. Researchers will track their vision, brain development, and overall health for up to 10 years to better predict outcomes. No new treatments are be…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC