Anterior pituitary gland disorder

Researchers are testing whether a higher dose of proton beam therapy can normalise hormone levels better than standard radiotherapy in people with functioning pituitary tumours, including acromegaly and Cushing's disease. Participants receive about six weeks of either standard-do…

This phase 3 trial tests a new long-acting octreotide injection (SYHX2008) in 154 adults with active acromegaly, a condition where the body makes too much growth hormone. The main goal is to see if the drug can bring hormone levels back to normal. Participants will receive the in…

This study tests whether a special PET scan (18FET) can find small pituitary tumors that standard MRI scans miss. About 30 adults with suspected hormone-secreting pituitary tumors will receive the scan. If it works, it could help doctors decide on surgery or radiation without nee…

This trial tests whether cabergoline, a drug that lowers the hormone prolactin, is safe for people with schizophrenia who have high prolactin levels due to antipsychotic medication. About 146 adults will receive either cabergoline or a placebo for 12 weeks, and researchers will c…

This study looks at how to safely place a breathing tube in people with acromegaly, a condition that can cause changes in the face and airway. It compares two methods: direct laryngoscopy and video laryngoscopy. The goal is to find which method gives a better view of the airway a…

This study looks at whether ultrasound can help doctors predict when placing a breathing tube will be difficult in people with acromegaly who are having pituitary surgery. Researchers will measure distances in the airway using ultrasound and compare them to standard physical exam…