Please sign in to follow a disease.

Annular epidermolytic ichthyosis

MONDO:0011870

Annular epidermolytic ichthyosis (AEI) is a rare clinical variant of epidermolytic ichthyosis (EI) characterized by the presence of a blistering phenotype at birth and the development from early infancy of annular polycyclic erythematous scales on the trunk and extremities.

Also known as: AEI, ichthyosis, annular epidermolytic, Ciehk, epidermolytic ichthyosis, annular, ichthyosis, cyclic, with epidermolytic hyperkeratosis

3 clinical trials for this condition and its sub-types, 0 tagged with Annular epidermolytic ichthyosis itself.

Follow this condition to get notified about new trials

Where it sits in the disease tree

Browse by category →

Part of

↑ Autosomal dominant epidermolytic ichthyosis (0)

Sub-types of Annular epidermolytic ichthyosis

Ichthyosis, annular epidermolytic 1 0 trials
Ichthyosis, annular epidermolytic, 2 0 trials

Including sub-types (3) Tagged with Annular epidermolytic ichthyosis (0)

Not yet finished but already full! 1 Completed 1 Terminated 1

New ointment shows promise for rare skin condition

Disease control Completed

This Phase 3 study tested an ointment called TMB-001 in 153 people aged 6 and older with X-linked or ARCI ichthyosis, conditions that cause dry, scaly, and cracked skin. Participants applied the ointment or a placebo daily for 12 weeks, with some continuing for maintenance. The g…

Phase 3 • Sponsor: LEO Pharma • Aim: Disease control

Last updated Jun 27, 2026 12:36 UTC

Annular epidermolytic ichthyosis

Where it sits in the disease tree

New ointment shows promise for rare skin condition