Anisocoria

MONDO:0007122

Unequal pupil size, which may represent a benign physiologic variant or a manifestation of disease. Pathologic anisocoria reflects an abnormality in the musculature of the iris (iris diseases) or in the parasympathetic or sympathetic pathways that innervate the pupil. Physiologic anisocoria refers to an asymmetry of pupil diameter, usually less than 2mm, that is not associated with disease.

Also known as: anisocoria, anisocoria (disease)

1 clinical trial for this condition and its sub-types, 1 tagged with Anisocoria itself.

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Where it sits in the disease tree

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↑ Hereditary disease (18187)

Including sub-types (1) Tagged with Anisocoria (1)

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Pupil differences in ICU patients may reveal hidden brain clues

Knowledge-focused Ongoing

This study looks at how often new pupil differences (one pupil larger than the other or not reacting normally) appear in adult intensive care patients. Researchers will review medical records from 2013 to 2024 to see what these changes mean for diagnosis, treatment, and patient o…

Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused

Last updated Jun 27, 2026 14:00 UTC

Anisocoria

Where it sits in the disease tree

Pupil differences in ICU patients may reveal hidden brain clues