Anaplastic oligoastrocytoma
MONDO:0016703An oligoastrocytoma characterized by the presence of increased cellularity, nuclear atypia, pleomorphism, and high mitotic activity.
Also known as: WHO grade III mixed glioma, aMOA, anaplastic mixed glioma, anaplastic oligoastrocytoma, AOAST
2840 clinical trials for this condition and its sub-types, 12 tagged with Anaplastic oligoastrocytoma itself.
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New combo therapy targets aggressive brain tumors in phase 2 trial
Disease control Recruiting nowThis study tests a more intense treatment for a fast-growing type of brain cancer called IDH wildtype glioma. It combines higher doses of radiation with the chemotherapy drug temozolomide to try to stop the tumor from growing longer. The trial will enroll 40 adults with this spec…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC
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New hope for aggressive brain tumors: avastin delivered directly to the brain
Disease control Recruiting nowThis study tests whether giving the drug bevacizumab (Avastin) directly into the brain's arteries, repeated over time, is safe and effective for people with recurrent glioblastoma or anaplastic astrocytoma. The approach uses a special infusion to bypass the blood-brain barrier. A…
Phase 1/2 • Sponsor: Northwell Health • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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New combo attack on recurrent brain tumors shows promise in early trial
Disease control Recruiting nowThis phase 2 trial tests a new way to deliver the cancer drug cetuximab directly into the brain's arteries, along with mannitol to open the blood-brain barrier, plus targeted radiation. It is for adults with recurrent glioblastoma or other aggressive brain tumors that have high l…
Phase 2 • Sponsor: Northwell Health • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Direct brain infusion trial offers new hope for kids with relapsed glioma
Disease control Recruiting nowThis study tests whether giving two drugs (cetuximab and bevacizumab) directly into the brain's blood vessels each month is safe and can shrink tumors or slow their growth. It includes children and young adults under 22 with certain types of brain tumors that have come back or no…
Phase 1/2 • Sponsor: University of Miami • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC