Alcohol dependence

This study will test whether living in a self-contained, AI-managed community (called a Microcity) can improve mental health and reduce addiction in adults with conditions like autism, ADHD, substance use disorders, and behavioral addictions. Up to 1 million participants will liv…

This study tests whether psilocybin (the active ingredient in magic mushrooms) combined with talk therapy can help people with severe alcohol use disorder reduce heavy drinking. Thirty-six adults who recently completed detox will receive either a high or low dose of psilocybin du…

This study tests whether repeated sessions of a gentle brain stimulation technique called tDCS can help people with alcohol use disorder drink less. Over 12 weeks, 312 participants will receive either real or sham tDCS in 5-day clusters each month. The goal is to see if this appr…

This study tests whether cannabidiol (CBD), a compound from cannabis, can reduce alcohol withdrawal symptoms and cravings in people with moderate-to-severe alcohol use disorder. 105 adults will stay in a hospital for 5 days, receive either CBD or a placebo alongside standard care…

This trial tests whether Snoezelen therapy—a calming, multisensory experience using lights, sounds, and textures—can improve health in adults with schizophrenia (including those needing institutional care) and women with alcohol dependence. Participants will attend 30-minute sess…

This study looks at whether adding alcohol-related smells to virtual reality scenes makes people with alcohol use disorder feel stronger cravings. Sixty participants will experience different combinations of visual scenes (neutral or alcohol-related) and smells (none or alcohol).…

This pilot study will test whether it is possible to run a larger trial comparing two ways to help people with alcohol use disorder. Sixty participants will either be invited to meet a therapist at the hospital for up to 10 sessions over 6 months, or receive guidance on finding a…