AIDS related complex
MONDO:0005639A prodromal phase of infection with the human immunodeficiency virus (HIV). Laboratory criteria separating aids-related complex (ARC) from aids include elevated or hyperactive B-cell humoral immune responses, compared to depressed or normal antibody reactivity in aids; follicular or mixed hyperplasia in arc lymph nodes, leading to lymphocyte degeneration and depletion more typical of aids; evolving succession of histopathological lesions such as localization of Kaposi's sarcoma, signaling the transition to the full-blown aids.
6 clinical trials for this condition and its sub-types, 1 tagged with AIDS related complex itself.
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Supercharged donor cells take on viruses after transplant
Disease control Recruiting nowThis study tests whether specially grown donor immune cells (viral-specific T-cells) can safely treat viral infections that often occur after a stem cell transplant. These infections can be serious and sometimes don't respond to standard antiviral drugs. The approach aims to boos…
Phase 1/2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Can donor cells stop viruses after transplant?
Disease control Recruiting nowThis study tests whether giving patients donor-derived immune cells (VSTs) on a regular schedule can prevent dangerous viral infections after a stem cell transplant. 180 participants will be randomly assigned to receive VSTs either on a fixed schedule or only when a virus is dete…
Phase 2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Texting for health: could a simple WhatsApp nudge boost HIV protection?
Prevention Recruiting nowThis study is testing whether weekly WhatsApp messages can help sexual and gender minorities in Brazil stay on track with HIV prevention (PrEP) and treatment (ART). Participants will be randomly assigned to receive either the messages or no messages for six months. The study will…
Sponsor: Oswaldo Cruz Foundation • Aim: Prevention
Last updated Aug 21, 2026 00:00 UTC
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Hidden kidney Super-Speed may undermine brain injury treatment
Knowledge-focused Recruiting nowThis study looks at a condition called augmented renal clearance (ARC), where the kidneys work too fast and flush out medications before they can help. It involves 512 adults in intensive care with severe brain injuries, strokes, seizures, or meningitis. Researchers will measure …
Sponsor: University of Alberta • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC