Adult-onset non-insulinoma persistent hyperinsulinemic hypoglycemia

MONDO:0017189

Diazoxide-resistant hyperinsulism (DRH) is form of congenital isolated hyperinsulinism caused by an abnormal insulin production by b-cells in the pancreas that can be diffuse or focal and is characterized by an excessive/ uncontrolled insulin secretion (inappropriate for the level of glycemia), recurrent episodes of profound hypoglycemia and resistance to medical management with diazoxide

Also known as: NI-PHH

1 clinical trial for this condition and its sub-types, 1 tagged with Adult-onset non-insulinoma persistent hyperinsulinemic hypoglycemia itself.

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Where it sits in the disease tree

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Part of

↑ Familial hyperinsulinism (12)

Including sub-types (1) Tagged with Adult-onset non-insulinoma persistent hyperinsulinemic hypoglycemia (1)

Completed 1

New PET scan tracer could shine a light on hidden pancreatic tumors

Diagnosis Completed

This study tested a new radioactive tracer called 18F-Exendin-4, used with PET/CT scans, to see if it can better detect insulinoma—a rare tumor in the pancreas that causes dangerously low blood sugar. Twenty participants with confirmed insulinoma received the tracer and underwent…

Sponsor: Sichuan Provincial People's Hospital • Aim: Diagnosis

Last updated Jun 27, 2026 08:11 UTC

Adult-onset non-insulinoma persistent hyperinsulinemic hypoglycemia

Where it sits in the disease tree

New PET scan tracer could shine a light on hidden pancreatic tumors