Adult hepatocellular carcinoma
MONDO:0016216Adult hepatocellular carcinoma is the most common primary liver cancer of adulthood. Derived from well-differentiated hepatocytes, it often develops from chronic liver cirrhosis which is most often due to hepatitis B and C virus or alcohol abuse. Symptoms are hepatic mass, abdominal pain and, in advanced stages, jaundice, cachexia and liver failure.
Also known as: hepatocellular cancer, adult HCC, adult hepatocellular carcinoma, adult hepatoma, adult primary carcinoma of liver cell, adult primary carcinoma of the liver cell, adult primary hepatocellular carcinoma, adult primary hepatoma
2914 clinical trials for this condition and its sub-types, 12 tagged with Adult hepatocellular carcinoma itself.
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Radiation boosts liver size, paving way for cancer surgery
Disease control OngoingThis study is for people with liver cancer who need surgery but don't have enough healthy liver left. Doctors use a special radiation treatment (Y90) to help the liver grow larger. Once the liver is big enough, patients can have surgery to remove the cancer. The study compares st…
Sponsor: Northwestern University • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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New drug combo aims to unleash immune system on liver cancer
Disease control OngoingThis phase 2 trial is testing whether two immunotherapy drugs, cobolimab and dostarlimab, can help people with advanced liver cancer. The drugs work by helping the immune system recognize and attack cancer cells. The study involves 42 adults whose liver cancer has spread or canno…
Phase 2 • Sponsor: University of Hawaii • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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New PET tracer could sharpen liver cancer diagnosis before surgery
Diagnosis OngoingThis study is testing a new imaging agent called 18F-FSPG to see if it can better detect liver cancer (hepatocellular carcinoma) and other liver tumors compared to standard PET scans. About 110 adults with liver cancer or benign liver tumors will receive the tracer before their s…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Diagnosis
Last updated Jun 27, 2026 13:00 UTC