Adrenal cortex carcinoma
MONDO:0006639A rare, usually large (greater than 5cm), malignant epithelial tumor arising from the adrenal cortical cells. Symptoms are usually related to the excessive production of hormones, and include Cushing's syndrome and virilism in women. Common sites of metastasis include liver, lung, bone, and retroperitoneal lymph nodes. Advanced radiologic procedures have enabled the detection of small tumors, resulting in the improvement of the 5-year survival.
Also known as: adrenal cortex cancer, adrenal cortical tumors, adrenal cortical tumours, adrenocortical cancer, cancer of the adrenal cortex, malignant adrenocortical tumor, malignant adrenocortical tumour, malignant neoplasm of adrenal cortex
2825 clinical trials for this condition and its sub-types, 42 tagged with Adrenal cortex carcinoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
Sub-types of Adrenal cortex carcinoma
-
Adrenocortical carcinoma, hereditary 0 trials
-
Experimental vaccine combo for rare adrenal cancers shows early promise but trial halted
Disease control Stopped earlyThis early-phase trial tested a new therapeutic vaccine (EO2401) combined with the immunotherapy drug nivolumab in 70 people with advanced adrenocortical carcinoma or malignant pheochromocytoma/paraganglioma. The goal was to see if the combination is safe and can shrink tumors or…
Phase 1/2 • Sponsor: Enterome • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
-
Cancer drug combo trial for kids halted early
Disease control Stopped earlyThis early-stage study tested a combination of two drugs, niraparib and dostarlimab, in children and teens (ages 6 months to 17 years) with solid tumors that had come back or were not responding to treatment. The goal was to find a safe dose and see if the drugs could shrink tumo…
Phase 1 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
-
Radioactive 'Smart Bomb' for tumours tested in early trial
Disease control Stopped earlyThis early-phase trial tested a radioactive drug designed to seek out and destroy cancer cells in people with advanced solid tumours that had stopped responding to other treatments. The drug targets a protein called IGF-1R found on many cancer cells. The study aimed to find a saf…
Phase 1 • Sponsor: Fusion Pharmaceuticals Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC