Adrenal cortex carcinoma
MONDO:0006639A rare, usually large (greater than 5cm), malignant epithelial tumor arising from the adrenal cortical cells. Symptoms are usually related to the excessive production of hormones, and include Cushing's syndrome and virilism in women. Common sites of metastasis include liver, lung, bone, and retroperitoneal lymph nodes. Advanced radiologic procedures have enabled the detection of small tumors, resulting in the improvement of the 5-year survival.
Also known as: adrenal cortex cancer, adrenal cortical tumors, adrenal cortical tumours, adrenocortical cancer, cancer of the adrenal cortex, malignant adrenocortical tumor, malignant adrenocortical tumour, malignant neoplasm of adrenal cortex
2825 clinical trials for this condition and its sub-types, 42 tagged with Adrenal cortex carcinoma itself.
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Sub-types of Adrenal cortex carcinoma
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Adrenocortical carcinoma, hereditary 0 trials
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Can a nationwide review unlock the secrets of a rare adrenal cancer?
Knowledge-focused CompletedThis study looks back at the medical records of 150 adults in Brazil diagnosed with adrenocortical carcinoma, a rare cancer of the adrenal glands. Researchers will collect details on age, gender, location, tumor stage, hormone activity, and treatments received since the year 2000…
Sponsor: Latin American Cooperative Oncology Group • Aim: Knowledge-focused
Last updated Sep 04, 2026 00:00 UTC
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Scientists investigate why adrenal tumors produce hormones
Knowledge-focused CompletedThis study looked at adrenal gland tumors to understand why they form, why some release extra hormones, and why some are cancerous. Researchers studied 690 people with known or suspected adrenal tumors. Participants underwent tests like blood draws, imaging scans, and urine colle…
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Sep 02, 2026 00:00 UTC
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Michigan study tests ways to boost genetic testing in cancer patients
Knowledge-focused CompletedThis study looked at whether a special website or coaching phone calls could help more people with a personal or family history of certain cancers get genetic testing. Over 800 participants were randomly assigned to one of these two methods or to standard care. The goal was to se…
Sponsor: University of Michigan Rogel Cancer Center • Aim: Knowledge-focused
Last updated Aug 20, 2026 00:00 UTC
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Urine test could replace repeated scans for adrenal tumors
Knowledge-focused CompletedThis study looked at 807 adults with adrenal tumors found by accident during scans for other reasons. Researchers compared the usual approach of repeat CT scans to a single urine steroid profile test to see which is more cost-effective for detecting cancer. The goal is to find a …
Sponsor: University Medical Center Groningen • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC