Acute liver failure
MONDO:0019542Rapid deterioration of liver function causing encephalopathy and coagulopathy. It results from damage to the liver parenchyma usually secondary to acetaminophen overdose or viral infections.
Also known as: acute hepatic failure, fulminant hepatic failure
25 clinical trials for this condition and its sub-types, 16 tagged with Acute liver failure itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Acute liver failure
-
Can more plasma exchange save lives in acute liver failure?
Disease control Not yet recruitingThis study compares high-volume versus standard plasma exchange in 60 patients with acute liver failure and brain swelling (cerebral edema). The goal is to see if exchanging more plasma (8-9 liters) reduces brain swelling faster and improves survival without a liver transplant. R…
Sponsor: Institute of Liver and Biliary Sciences, India • Aim: Disease control
Last updated Jun 26, 2026 19:19 UTC
-
New study aims to predict who will survive acute liver failure
Knowledge-focused Not yet recruitingThis study will follow 400 people with acute liver failure to understand what causes it and what factors affect survival. Researchers will analyze blood and liver tissue samples to find clues. The goal is to create a model that helps doctors decide when a liver transplant is need…
Sponsor: Li-Ying Sun • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC