Acute asthma

This study tests whether combining high-flow nasal oxygen with a vibrating membrane nebulizer helps patients with asthma or COPD flare-ups reach their target oxygen levels better than standard care with a nebulizer mask. Emergency medical services will compare a group receiving u…

This study looks at whether a dedicated asthma flare-up clinic can improve how adults manage their asthma after a severe attack. About 230 participants will either get structured in-person follow-up visits or phone check-ins. Researchers will compare rates of future asthma attack…

This study tests whether adding dupilumab (Dupixent) to standard asthma care can prevent asthma attacks in 240 urban children and teens aged 6–17 with severe, allergy-driven asthma. Participants receive either dupilumab or a placebo for 12 months. The main goal is to see if the d…

This Phase 3 trial tests dexpramipexole, an oral tablet, as an add-on treatment for people with eosinophilic asthma that is not well controlled. About 600 participants aged 12 and older will receive either the drug or a placebo for 24 weeks. The study measures improvements in lun…

This study looks at how dupilumab, a drug for severe asthma, is actually used by patients in France. Researchers will analyze health records of about 35,000 people to describe their characteristics, healthcare costs, and steroid use before and after starting the drug. The goal is…