Acromegaly
MONDO:0019933Acromegaly is an acquired disorder related to excessive production of growth hormone (GH) and characterized by progressive somatic disfigurement (mainly involving the face and extremities) and systemic manifestations.
Also known as: Growth hormone excess, pituitary giant, somatotroph adenoma
29 clinical trials for this condition and its sub-types, 29 tagged with Acromegaly itself.
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Can a stronger radiation dose fix hormone overload?
Disease control Not yet recruitingResearchers are testing whether a higher dose of proton beam therapy can normalise hormone levels better than standard radiotherapy in people with functioning pituitary tumours, including acromegaly and Cushing's disease. Participants receive about six weeks of either standard-do…
Phase 3 • Sponsor: University College, London • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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New Long-Acting shot aims to tame acromegaly in phase 3 trial
Disease control Not yet recruitingThis phase 3 trial tests a new long-acting octreotide injection (SYHX2008) in 154 adults with active acromegaly, a condition where the body makes too much growth hormone. The main goal is to see if the drug can bring hormone levels back to normal. Participants will receive the in…
Phase 3 • Sponsor: CSPC ZhongQi Pharmaceutical Technology Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New scan could spot invisible brain tumors
Diagnosis Not yet recruitingThis study tests whether a special PET scan (18FET) can find small pituitary tumors that standard MRI scans miss. About 30 adults with suspected hormone-secreting pituitary tumors will receive the scan. If it works, it could help doctors decide on surgery or radiation without nee…
Phase 2 • Sponsor: University Hospital, Lille • Aim: Diagnosis
Last updated Jun 27, 2026 12:29 UTC
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Which intubation method works best for acromegaly patients?
Knowledge-focused Not yet recruitingThis study looks at how to safely place a breathing tube in people with acromegaly, a condition that can cause changes in the face and airway. It compares two methods: direct laryngoscopy and video laryngoscopy. The goal is to find which method gives a better view of the airway a…
Sponsor: Muzaffer GENCER • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Can ultrasound make intubation safer for acromegaly patients?
Knowledge-focused Not yet recruitingThis study looks at whether ultrasound can help doctors predict when placing a breathing tube will be difficult in people with acromegaly who are having pituitary surgery. Researchers will measure distances in the airway using ultrasound and compare them to standard physical exam…
Sponsor: Başakşehir Çam & Sakura City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC