Acromegaly

Acromegaly is a rare condition where the pituitary gland makes too much growth hormone, causing bones and tissues to enlarge. Researchers are testing a long-acting octreotide injection called SYHX2008 in 78 adults with active acromegaly. Participants receive either the new inject…

This trial is testing whether a new, once-monthly injection of octreotide (CAM2029) can help people with acromegaly, a condition where the body makes too much growth hormone. Participants will receive either the study drug or a placebo for six months. The main goal is to see if t…

This study tested a monthly injection called CAM2029 (octreotide) in 135 adults with acromegaly, a condition where the body makes too much growth hormone. The goal was to see if the drug is safe and keeps hormone levels under control over 12 months. Participants had already been …

This study tested a drug called pegvisomant in children aged 2 to 18 with gigantism, a condition where the body makes too much growth hormone. The goal was to see if the drug could safely lower hormone levels and slow down abnormal growth. Participants received daily injections a…

This study tested whether a three-week ketogenic diet could improve hormone and metabolic measures in 26 adults with active acromegaly, compared to a Mediterranean diet. Participants followed each diet for three weeks, with a two-week break in between. The main goal was to see ch…

This study looked at whether a standard glucose tolerance test (drinking a sugary solution) can reliably diagnose acromegaly, a condition caused by too much growth hormone. Researchers tested 109 people, some with acromegaly and some without, giving them two glucose tests and one…

This early-stage trial in 18 healthy adults compares a new octreotide tablet (T25) with an existing capsule (MYCAPSSA) to see how much drug gets into the blood. It also checks whether a high-fat meal changes absorption of the tablet. Participants take single doses under fasting o…

This observational study tracks patients in Korea who have been prescribed Somavert (pegvisomant) for acromegaly, a condition caused by too much growth hormone. Researchers will monitor side effects and whether patients show clinical improvement during routine treatment. The goal…

This study tested a new software tool called ACRODAT that helps doctors track disease activity in people with acromegaly. The tool looks at five key factors like hormone levels, symptoms, and quality of life. Researchers compared patients whose doctors used ACRODAT to those recei…

This study followed 20 adults with acromegaly for one year after pituitary surgery. Researchers measured growth hormone and related substances at several time points to see if early test results could predict whether the disease goes into remission. The goal is to find better way…