Acrokeratosis verruciformis

MONDO:0007048

A rare genetic skin keratinization disorder with an autosomal dominant mode of inheritance. It is characterized by numerous flesh-colored warty papules on the back of the hands, medial aspect of the feet, knees, and elbows.

Also known as: AKV of Hopf, Hopf disease, acrokeratosis verruciformis, acrokeratosis verruciformis of Hopf, AKV

1 clinical trial for this condition and its sub-types, 1 tagged with Acrokeratosis verruciformis itself.

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Where it sits in the disease tree

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Part of

↑ Hereditary skin disorder (885) ↑ Keratosis (30)

Including sub-types (1) Tagged with Acrokeratosis verruciformis (1)

Terminated 1

Cream combo tested for scalp bumps in men of african descent

Disease control Stopped early

This study tested Duobrii, a prescription cream that combines a strong steroid with a retinoid, for treating early-mild acne keloidalis nuchae (AKN) — a chronic scalp condition causing bumps and scarring, mainly in men of African descent. The trial planned to enroll 15 adults wit…

Phase 3 • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Disease control

Last updated Jun 27, 2026 07:56 UTC

Acrokeratosis verruciformis

Where it sits in the disease tree

Cream combo tested for scalp bumps in men of african descent