Acquired purpura fulminans
MONDO:0018854A life-threatening, rapidly progressive thrombotic disorder affecting mainly neonates and children that is characterized by purpuric skin lesions and disseminated intravascular coagulation. PF may progress rapidly to multi-organ failure caused by thrombotic occlusion of small and medium-sized blood vessels. There are two forms of PF that are classified according to triggering mechanisms: acute infectious (the most common form), and idiopathic PF.
Also known as: acquired PF, acquired purpura fulminans
14 clinical trials for this condition and its sub-types, 0 tagged with Acquired purpura fulminans itself.
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Hospital study aims to find best way to monitor blood thinner dosing
Disease control CompletedThis study compares two methods for monitoring the blood thinner heparin in hospitalized patients with blood clots. One method uses a standard clotting test (PTT), while the other uses a newer test (anti-Xa). The goal is to see which method helps patients reach the right blood th…
Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated Sep 21, 2026 20:00 UTC
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Battlefield plasma goes civil: can a powder save trauma victims?
Disease control CompletedThis study tested a freeze-dried plasma product that can be mixed with water in 6 minutes, avoiding the long thaw time of standard plasma. It included 42 trauma patients with severe bleeding who needed blood transfusions. The goal was to see if faster plasma delivery could improv…
Phase 3 • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New blood product could cut transfusions in major surgeries
Disease control CompletedThis study tested a pathogen-reduced version of cryoprecipitate, a blood product that helps blood clot, in 208 patients undergoing liver transplant or heart surgery. The goal was to see if having this product readily available could stop bleeding early and reduce the need for oth…
Phase 4 • Sponsor: Weill Medical College of Cornell University • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Teens with blood disorders share their stories in new study
Knowledge-focused CompletedThis study interviewed 15 children aged 12 to 21 who have bleeding or clotting disorders. Researchers asked about their quality of life, confidence in managing their condition, and how they view the care they receive. The goal is to better understand the real-life challenges thes…
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC