Acquired hemophilia A
MONDO:0035735An acquired form of hemophilia A, resulting in spontaneous bleeding in individuals with no history of bleeding disorders. It is believed to be caused by spontaneous inhibition of clotting factor VIII by autoantibodies, and is usually associated with other autoimmune conditions.
Also known as: AHA
18 clinical trials for this condition and its sub-types, 6 tagged with Acquired hemophilia A itself.
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Can a lab-made antibody stop bleeding in a rare blood disorder?
Disease control Not yet recruitingResearchers are testing denecimig, an experimental antibody given as an injection under the skin, in adults newly diagnosed with acquired haemophilia A. This rare condition causes the immune system to attack a clotting protein, leading to sudden and sometimes severe bleeding. The…
Phase 3 • Sponsor: Novo Nordisk A/S • Aim: Disease control
Last updated Sep 21, 2026 16:00 UTC
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Can a new drug stop bleeding in acquired hemophilia a?
Disease control Not yet recruitingThis trial tests whether an experimental drug called bometase alfa can safely stop bleeding episodes in people with acquired hemophilia A, a rare condition where the immune system attacks a key blood-clotting protein. About 20 adults with active bleeding will receive the drug by …
Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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Ginger vs. heavy periods: a natural approach for women with bleeding disorders
Symptom relief Not yet recruitingThis study tests whether taking ginger powder for the first three days of each period can reduce heavy menstrual bleeding in women with coagulation disorders (bleeding problems). 74 women will be randomly assigned to receive either ginger or a placebo for six cycles. The goal is …
Early phase 1 • Sponsor: University of Valladolid • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Teaching kids with hemophilia to brush better: a new study
Knowledge-focused Not yet recruitingThis study will enroll 70 Egyptian children with hemophilia to see if an oral health education program improves their dental health and quality of life. The program teaches proper oral care based on guidelines from dental and hemophilia organizations. Researchers will measure cav…
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC