Acquired hemophilia A
MONDO:0035735An acquired form of hemophilia A, resulting in spontaneous bleeding in individuals with no history of bleeding disorders. It is believed to be caused by spontaneous inhibition of clotting factor VIII by autoantibodies, and is usually associated with other autoimmune conditions.
Also known as: AHA
18 clinical trials for this condition and its sub-types, 6 tagged with Acquired hemophilia A itself.
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Can a lab-made antibody stop bleeding in a rare blood disorder?
Disease control Not yet recruitingResearchers are testing denecimig, an experimental antibody given as an injection under the skin, in adults newly diagnosed with acquired haemophilia A. This rare condition causes the immune system to attack a clotting protein, leading to sudden and sometimes severe bleeding. The…
Phase 3 • Sponsor: Novo Nordisk A/S • Aim: Disease control
Last updated Sep 21, 2026 21:00 UTC
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Can a new drug stop bleeding in acquired hemophilia a?
Disease control Not yet recruitingThis trial tests whether an experimental drug called bometase alfa can safely stop bleeding episodes in people with acquired hemophilia A, a rare condition where the immune system attacks a key blood-clotting protein. About 20 adults with active bleeding will receive the drug by …
Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC