Acquired hemophilia
MONDO:0019139Acquired hemophilia is a bleeding disorder that interferes with the body's blood clotting process. Signs and symptoms include prolonged bleeding, frequent nosebleeds, bruising throughout the body, solid swellings of congealed blood (hematomas), hematuria, and gastrointestinal or urologic bleeding. Acquired hemophilia occurs when the body's immune system attacks and disables a certain protein that helps the blood clot. About half of the cases are associated with other conditions, such as pregnancy, autoimmune disease, cancer, skin diseases, or allergic reactions to medications.
Also known as: acquired hemophilia, hemophilia, acquired
20 clinical trials for this condition and its sub-types, 2 tagged with Acquired hemophilia itself.
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Sub-types of Acquired hemophilia
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Acquired hemophilia A 6 trials
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Acquired factor XI deficiency 0 trials
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Acquired hemophilia B 0 trials
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Can a lab-made antibody stop bleeding in a rare blood disorder?
Disease control Not yet recruitingResearchers are testing denecimig, an experimental antibody given as an injection under the skin, in adults newly diagnosed with acquired haemophilia A. This rare condition causes the immune system to attack a clotting protein, leading to sudden and sometimes severe bleeding. The…
Phase 3 • Sponsor: Novo Nordisk A/S • Aim: Disease control
Last updated Sep 21, 2026 13:00 UTC
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Can a new drug stop bleeding in acquired hemophilia a?
Disease control Not yet recruitingThis trial tests whether an experimental drug called bometase alfa can safely stop bleeding episodes in people with acquired hemophilia A, a rare condition where the immune system attacks a key blood-clotting protein. About 20 adults with active bleeding will receive the drug by …
Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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Ginger vs. heavy periods: a natural approach for women with bleeding disorders
Symptom relief Not yet recruitingThis study tests whether taking ginger powder for the first three days of each period can reduce heavy menstrual bleeding in women with coagulation disorders (bleeding problems). 74 women will be randomly assigned to receive either ginger or a placebo for six cycles. The goal is …
Early phase 1 • Sponsor: University of Valladolid • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Teaching kids with hemophilia to brush better: a new study
Knowledge-focused Not yet recruitingThis study will enroll 70 Egyptian children with hemophilia to see if an oral health education program improves their dental health and quality of life. The program teaches proper oral care based on guidelines from dental and hemophilia organizations. Researchers will measure cav…
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC