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Hereditary spastic paraplegia

Hereditary spastic paraplegias (HSP) comprise a genetically and clinically heterogeneous group of neurodegenerative disorders characterized by progressive spasticity and hyperreflexia of the lower limbs.

27 trials tagged with this condition →

Complex hereditary spastic paraplegia 1 trial · 7 incl. sub-types Sub-types →
Hereditary spastic paraplegia 50 3 trials
Hereditary spastic paraplegia 3A 2 trials
Hereditary spastic paraplegia 4 2 trials
Hereditary spastic paraplegia 5A 2 trials
Hereditary spastic paraplegia 47 1 trial
Hereditary spastic paraplegia 51 1 trial
Hereditary spastic paraplegia 52 1 trial
Hereditary spastic paraplegia 7 1 trial
ADAR-related hereditary spastic paraplegia 0 trials
Charcot-Marie-Tooth disease type 5 0 trials
IFIH1-related hereditary spastic paraplegia 0 trials
RNASEH2B-related hereditary spastic paraplegia 0 trials
Early-onset progressive neurodegeneration-blindness-ataxia-spasticity syndrome 0 trials
Hereditary spastic paraplegia 10 0 trials
Hereditary spastic paraplegia 13 0 trials
Hereditary spastic paraplegia 14 0 trials
Hereditary spastic paraplegia 16 0 trials
Hereditary spastic paraplegia 2 0 trials
Hereditary spastic paraplegia 30 0 trials Sub-types →
Hereditary spastic paraplegia 31 0 trials
Hereditary spastic paraplegia 33 0 trials
Hereditary spastic paraplegia 35 0 trials
Hereditary spastic paraplegia 48 0 trials
Hereditary spastic paraplegia 56 0 trials
Hereditary spastic paraplegia 6 0 trials
Hereditary spastic paraplegia 77 0 trials
Macrocephaly-spastic paraplegia-dysmorphism syndrome 0 trials
Mast syndrome 0 trials
Pure hereditary spastic paraplegia 0 trials Sub-types →
Pure or complex hereditary spastic paraplegia 0 trials
Spastic paraplegia 72b, autosomal recessive 0 trials
Spastic paraplegia 79A, autosomal dominant, with ataxia 0 trials
Spastic paraplegia 80, autosomal dominant 0 trials
Spastic paraplegia 81, autosomal recessive 0 trials
Spastic paraplegia 82, autosomal recessive 0 trials
Spastic paraplegia 83, autosomal recessive 0 trials
Spastic paraplegia 87, autosomal recessive 0 trials
Spastic paraplegia 88, autosomal dominant 0 trials
Spastic paraplegia 89, autosomal recessive 0 trials
Spastic paraplegia 90A, autosomal dominant 0 trials
Spastic paraplegia 90B, autosomal recessive 0 trials
Spastic paraplegia 91, autosomal dominant, with or without cerebellar ataxia 0 trials
Spastic paraplegia 92, autosomal recessive 0 trials
Spastic paraplegia 93, autosomal recessive 0 trials