New drug combo tested for Tough-to-Treat ovarian cancer

NCT ID NCT05198804

Summary

This study tested a new drug called ZN-c3, both by itself and combined with an existing drug (niraparib), for women with advanced ovarian cancer that had stopped responding to platinum chemotherapy. The main goals were to find safe doses and see if the treatments could shrink tumors. It involved 117 women whose cancer had progressed despite prior treatments.

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Contacts and locations

Locations

  • Arizona Oncology Associates (Wilmot HOPE) - USOR

    Tucson, Arizona, 85711, United States

  • Centre Georges François Leclerc

    Dijon, France

  • Centre Hospitalier Lyon Sud

    Saint-Genis-Laval, France

  • Centre Oscar Lambret

    Lille, France

  • EDOG - Institut Claudius Regaud

    Toulouse, France

  • ICANS - Institut de cancérologie Strasbourg Europe

    Strasbourg, France

  • Institut Gustave Roussy

    Villejuif, France

  • Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • MD Anderson Cancer Center, Gynecologic Oncology Center

    Texas City, Texas, 77030, United States

  • Mount Sinai Comprehensive Cancer Center

    Miami Beach, Florida, 33140, United States

  • Optimum Clinical Research Group- Women's Oncology

    Albuquerque, New Mexico, 87109, United States

  • Rocky Mountain Cancer Centers

    Aurora, Colorado, 80012, United States

  • Rutgers New Jersey Medical School

    Newark, New Jersey, 07103, United States

  • Spectrum Health System

    Grand Rapids, Michigan, 49503, United States

  • Texas Oncology-Fort Worth Cancer Center

    Fort Worth, Texas, 76104, United States

  • The Blavatnik Family - Chelsea Medical Center at Mount Sinai

    New York, New York, 10011, United States

  • University of Colorado

    Aurora, Colorado, 80045, United States

  • University of Virginia

    Charlottesville, Virginia, 22908, United States

  • Virginia Cancer Specialists

    Fairfax, Virginia, 22031, United States

  • Virginia Commonwealth University

    Richmond, Virginia, 23298, United States

  • Willamette Valley Cancer Institute and Research Center

    Eugene, Oregon, 97401, United States

  • Women and Infants Hospital of Rhode Island

    Providence, Rhode Island, 02905, United States

Conditions

Explore the condition pages connected to this study.