New drug combo tested for Hard-to-Treat cancers

NCT ID NCT05859464

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 30 times

Summary

This study tested an experimental drug called ZL-1218, alone or with another cancer drug, in 34 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check the drug's safety, find the right dose, and see if it could shrink tumors. The trial was stopped early, so results are limited.

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Contacts and locations

Locations

  • Zai Lab Site 1001

    Shanghai, 200123, China

  • Zai Lab Site 1002

    Hangzhou, 310009, China

  • Zai Lab Site 2001

    Hackensack, New Jersey, 07601, United States

  • Zai Lab Site 2002

    New York, New York, 10029, United States

  • Zai Lab Site 2003

    Spokane, Washington, 99208, United States

  • Zai Lab Site 2005

    Irvine, California, 92618, United States

  • Zai Lab Site 2007

    Detroit, Michigan, 48201, United States

  • Zai Lab Site 8001

    Barcelona, Barcelona, 8035, Spain

  • Zai Lab Site 8002

    Valencia, Valencia, 46009, Spain

  • Zai Lab Site 8003

    Seville, Sevilla, 41009, Spain

  • Zai Lab Site 8004

    Pozuelo de Alarcón, Madrid, 28223, Spain

  • Zai Lab Site 8005

    Barcelona, Barcelona, 8023, Spain

  • Zai Lab Site 8006

    Valencia, Valencia, 46010, Spain

  • Zai Lab Site 8007

    Madrid, Madrid, 28040, Spain

  • Zai Lab Site 8008

    Madrid, Madrid, 28050, Spain

Conditions

Explore the condition pages connected to this study.