Could zinc and a liver pill help newborns beat jaundice faster?

NCT ID NCT06517862

Recruiting now Disease control Sponsor: Amira Adel Fouly Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving oral zinc sulfate and ursodeoxycholic acid alongside standard light therapy can help clear jaundice faster in newborns. About 80 babies with non-hemolytic jaundice will receive one of two doses of zinc, or the liver drug UDCA, plus phototherapy. The goal is to see if these add-ons lower bilirubin levels and shorten the time babies need treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: zinc sulfate and ursodeoxycholic acid
What this could lead to: If successful, this could provide a safe, simple way to speed up jaundice treatment in newborns, reducing time under phototherapy and hospital stays.
What could go wrong: This is a small, early-phase trial with only 80 babies, so results may not apply broadly. Side effects from the drugs are possible, and the benefit over phototherapy alone may be modest.

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Conditions

The condition(s) this trial relates to.

hyperbilirubinemia Hyperbilirubinemia, Neonatal transient familial neonatal hyperbilirubinemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEONATAL HYPERBILIRUBINEMIA

Contacts and locations

Locations

Neonatal Intensive Care Unit (NICU) of Ain Shams University Hospitals
RECRUITING

Cairo, Cairo Governorate, Egypt

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