New combo therapy aims to slow resistant prostate cancer
NCT ID NCT04986423
First seen May 09, 2026 · Last updated May 15, 2026 · Updated 1 time
Summary
This study tests whether adding an experimental drug (ZEN003694) to the standard treatment enzalutamide can help men with a certain type of advanced prostate cancer that has stopped responding to another drug (abiraterone). About 200 men will be randomly assigned to receive either the combination or enzalutamide alone. The goal is to see if the combination delays cancer growth or death.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Anhui Provincial Hospital
RECRUITINGHefei, Anhui, 230002, China
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BRCR Global
RECRUITINGPlantation, Florida, 33322, United States
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California Research Institute
RECRUITINGLos Angeles, California, 90027, United States
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Chongqing Cancer Hospital
RECRUITINGChongqing, Chongqing Municipality, 400030, China
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Colorado Urology
RECRUITINGLakewood, Colorado, 80228, United States
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D&H Cancer Research Center, LLC
RECRUITINGMargate, Florida, 33063, United States
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First Hospital of Shanxi Medical University
RECRUITINGTaiyuan, Shanxi, 030001, China
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Fudan University Shanghai Cancer Center
RECRUITINGShanghai, Shanghai Municipality, 200032, China
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Hematology Oncology Clinic
WITHDRAWNBaton Rouge, Louisiana, 70809, United States
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Henan Cancer Hospital
RECRUITINGZhengzhou, Henan, 450000, China
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Hubei Cancer Hospital
RECRUITINGWuhan, Hubei, 430079, China
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Hunan Cancer Hospital
RECRUITINGChangsha, Hunan, 410006, China
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Innovative Clinical Research Institute
RECRUITINGWhittier, California, 90603, United States
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Liaoning Cancer Hospital
WITHDRAWNShenyang, Liaoning, 110042, China
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Maryland Oncology Hematology, P.A.
RECRUITINGColumbia, Maryland, 21044, United States
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Messino Cancer Center
RECRUITINGAsheville, North Carolina, 28806, United States
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Nanjing Drum Tower Hospital
RECRUITINGNanjing, Jiangsu, 210008, China
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Northwest Cancer Specialists, P.C.
RECRUITINGPortland, Oregon, 97223, United States
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Seattle Cancer Care Alliance
RECRUITINGSeattle, Washington, 98109, United States
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Shanghai Tenth People's Hospital
RECRUITINGShanghai, Shanghai Municipality, 200072, China
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Sichuan Provincial People's Hospital
RECRUITINGChengdu, Sichuan, 610072, China
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Texas Oncology - Central South
RECRUITINGAustin, Texas, 78731, United States
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The First Affiliated Hospital of Xi'an Jiaotang University
RECRUITINGXi'an, Shaanxi, 71000, China
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The First Affiliated Hospital of Xiamen University
RECRUITINGXiamen, Fujian, 361003, China
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Tongji Hospital of Tongji Medical College, Huazhong University of Science & Technology
RECRUITINGWuhan, Hubei, 430030, China
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94158, United States
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University of Michigan Rogel Cancer Center
RECRUITINGAnn Arbor, Michigan, 48109, United States
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Urology Associates, P.C.
RECRUITINGNashville, Tennessee, 37209, United States
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Virginia Cancer Specialists
RECRUITINGFairfax, Virginia, 22031, United States
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Weill Cornell Medical College - New York Presbyterian Hospital
COMPLETEDNew York, New York, 10065, United States
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Zhejiang Provincial People's Hospital
RECRUITINGHangzhou, Zhejiang, 310014, China
Conditions
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