Could a Once-a-Week pill lift depression?
NCT ID NCT07115329
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new oral drug called zelquistinel to see if it can reduce symptoms of major depressive disorder in adults. About 164 people aged 18 to 64 will take either the drug or a placebo once a week for 6 weeks. Researchers will measure changes in depression severity using standard rating scales and monitor for any medical problems.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Adams Clinical
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Adams Clinical Dallas
NOT_YET_RECRUITINGDeSoto, Texas, 75115, United States
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Anderson Clinical Research
RECRUITINGRedlands, California, 92374, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Aqualane Clinical Research
RECRUITINGNaples, Florida, 34105, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Catalina Research Institute, LLC
RECRUITINGMontclair, California, 91763, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Clinical Neuroscience Solutions, Inc
NOT_YET_RECRUITINGJacksonville, Florida, 32256, United States
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Continental Clinical Solutions
RECRUITINGTowson, Maryland, 21204, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Del Sol Research Management
RECRUITINGTucson, Arizona, 85710, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Denali Health Atlanta, LLC
RECRUITINGStone Mountain, Georgia, 30038, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Elevate Synapsis, LLC
RECRUITINGAtascocita, Texas, 77346, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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EmVenio Research
RECRUITINGChicago, Illinois, 60622, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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EquiPath Health and Research Tampa Bay, LLC
RECRUITINGRiverview, Florida, 33578, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Excell Research, Inc
RECRUITINGOceanside, California, 92056, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IMA Clinical Research - NYC Midtown
RECRUITINGNew York, New York, 10036, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IMA Clinical Research - NYC Uptown
RECRUITINGNew York, New York, 10128, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Insight Clinical Trials LLC
NOT_YET_RECRUITINGIndependence, Ohio, 44131, United States
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Lehigh Center for Clinical Research
NOT_YET_RECRUITINGAllentown, Pennsylvania, 18103, United States
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Lumos Clinical Research Center
RECRUITINGSan Jose, California, 95124, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Neurobehavioral Research, Inc
NOT_YET_RECRUITINGCedarhurst, New York, 11516, United States
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Neuroscience Research Institute
RECRUITINGWest Palm Beach, Florida, 33407, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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NoesisPharma, LLC
RECRUITINGPhoenix, Arizona, 85028, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Premier Clinical Research Institute Inc
NOT_YET_RECRUITINGMiami, Florida, 33122, United States
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Psychiatric Consultants, PC
RECRUITINGFranklin, Tennessee, 37067, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Rochester Center for Behavioral Medicine
RECRUITINGRochester Hills, Michigan, 48307, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Scranton Medical Institute, LLC
TERMINATEDMoosic, Pennsylvania, 18507, United States
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Studyops Inc
RECRUITINGSan Francisco, California, 94102, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sunstone Therapies
RECRUITINGRockville, Maryland, 20850, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sunwise Clinical Research
NOT_YET_RECRUITINGWalnut Creek, California, 94596, United States
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Synapsis Bio
NOT_YET_RECRUITINGAtascocita, Texas, 77346, United States
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Tandem Clinical Research
RECRUITINGMetairie, Louisiana, 70006, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UNC Health Rex
NOT_YET_RECRUITINGRaleigh, North Carolina, 27607, United States
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Vitalix Clinical
RECRUITINGWorcester, Massachusetts, 01608, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••