New weekly pill could ease depression symptoms

NCT ID NCT06547489

Recruiting now Symptom relief Sponsor: Syndeio Biosciences, Inc Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 4 times

Summary

This study tests whether a new oral drug called zelquistinel can reduce depression symptoms in adults with major depressive disorder. Participants take one tablet weekly for 6 weeks and have their depression severity checked at each clinic visit. The trial compares the drug against a placebo to see if it works and is safe.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER

Contacts and locations

Locations

Andes Clinical Research
RECRUITING

Orem, Utah, 84097, United States
Austin Clinical Trial Partners
RECRUITING

Austin, Texas, 78737, United States
Baylor College of Medicine, Psychiatry and Behavioral Sciences
WITHDRAWN

Houston, Texas, 77030, United States
Boston Clinical Trials
WITHDRAWN

Boston, Massachusetts, 02131, United States
CalNeuro Research Group
RECRUITING

Los Angeles, California, 90025, United States
CenExel iRS (iResearch Savannah)
RECRUITING

Savannah, Georgia, 31405, United States
Clinical Neuroscience Solutions, Inc.
RECRUITING

Jacksonville, Florida, 32256, United States
Clinical Neuroscience Solutions, Inc.
RECRUITING

Orlando, Florida, 32801, United States
Clinical Neuroscience Solutions, Inc.
WITHDRAWN

Memphis, Tennessee, 38119, United States
Clinical Trials of Texas LLC
WITHDRAWN

San Antonio, Texas, 78229, United States
D&H Pompano Research Center, LLC
RECRUITING

Margate, Florida, 33063, United States
Grayline Research Center
RECRUITING

Wichita Falls, Texas, 76309, United States
InSite Clinical Research, LLC
RECRUITING

DeSoto, Texas, 75115, United States
Insight Clinical Trials LLC
RECRUITING

Independence, Ohio, 44131, United States
Irvine Clinical Research
RECRUITING

Irvine, California, 92614, United States
KUMC-Wichita
WITHDRAWN

Wichita, Kansas, 66160, United States
Lehigh Center for Clinical Research
RECRUITING

Allentown, Pennsylvania, 18103, United States
MCB Clinical Research Centers, Inc.
RECRUITING

Colorado Springs, Colorado, 80910, United States
Mayflower Clinical
RECRUITING

Russells Mills, Massachusetts, 02747, United States
Miami Dade Medical Research Institute
RECRUITING

Miami, Florida, 33176, United States
Mountain View Clinical Research
RECRUITING

Denver, Colorado, 80209, United States
Neurobehavioral Research, Inc.
RECRUITING

Cedarhurst, New York, 11516, United States
Northwest Clinical Research Center
WITHDRAWN

Bellevue, Washington, 98007, United States
Pacific Clinical Research Management Group LLC
TERMINATED

Upland, California, 91786, United States
Premier Clinical Research Institute, Inc.
RECRUITING

Miami, Florida, 33122, United States
Quantum Research Associates Corp.
ACTIVE_NOT_RECRUITING

Louisville, Kentucky, 40218, United States
Revive Research Institute
WITHDRAWN

Elgin, Illinois, 60123, United States
Sooner Clinical Research, Inc.
WITHDRAWN

Oklahoma City, Oklahoma, 73116, United States
Sunwise Clinical Research LLC
RECRUITING

Walnut Creek, California, 94549, United States
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35294, United States
University of Alabama at Birmingham-Huntsville
ACTIVE_NOT_RECRUITING

Huntsville, Alabama, 35801, United States
University of Connecticut School of Medicine Psychiatry Department
RECRUITING

Farmington, Connecticut, 06030, United States
Vector Clinical Trials
ACTIVE_NOT_RECRUITING

Las Vegas, Nevada, 89128, United States
Wr-Pri, Llc
WITHDRAWN

Encino, California, 91316, United States

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