New study: can zavegepant stop migraines when prevention Isn't enough?

NCT ID NCT06401642

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 28 times

Summary

This study looks at whether zavegepant (Zavzpret), a nasal spray already approved for migraines, works well and is safe for people who are already taking a CGRP-targeting preventive medication. About 200 adults with 2 to 8 migraines per month will use the spray at the start of an attack. Researchers will measure headache relief and ability to function within 2 and 4 hours, and track any side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Mayo Clinic in Arizona

    RECRUITING

    Phoenix, Arizona, 85254, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

Explore the condition pages connected to this study.