New study: can zavegepant stop migraines in patients already on prevention?

NCT ID NCT06401642

First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 30 times

Summary

This study looks at whether zavegepant (Zavzpret), a nasal spray already approved for migraines, works well and is safe for people who are also taking CGRP-targeting preventive medications. About 200 adults with 2-8 migraines per month will take zavegepant during an attack and report headache relief and side effects. The goal is to see if adding this rescue treatment helps when prevention alone isn't enough.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Mayo Clinic in Arizona

    RECRUITING

    Phoenix, Arizona, 85254, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

Explore the condition pages connected to this study.