New pill could clear skin in kids with psoriasis – trial underway

NCT ID NCT07250802

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial tests whether zasocitinib, an oral medication, can safely and effectively treat moderate-to-severe plaque psoriasis in children and teens aged 4 to 17. The study involves 110 participants and lasts up to 4 years. In the first part, some receive the drug and others a placebo for 16 weeks; after that, everyone gets the drug. The goal is to see if the drug can clear or nearly clear the skin and reduce psoriasis severity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Zasocitinib (a pill that targets inflammation)

What this could lead to

If it works, this could provide a new treatment option for children and teens with moderate-to-severe plaque psoriasis, potentially clearing or nearly clearing their skin.

What could go wrong

This is still a clinical trial, so it's not yet proven to work in children. Possible side effects include infections or other inflammatory-related issues. The study is relatively small (110 participants), so results may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

psoriasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • "DERMED" Centrum Medyczne Sp. z o. o.

    RECRUITING

    Lodz, 90-265, Poland

    Contact

    Contact Email: •••••@•••••

  • Apex Clinical Research Center, LLC

    RECRUITING

    Canton, Ohio, 44718, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Apex Clinical Research Center, LLC

    RECRUITING

    Mayfield Heights, Ohio, 44124-4005, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Arlington Dermatology

    RECRUITING

    Rolling Meadows, Illinois, 60008-3811, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Beijing Children Hospital, Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 100045, China

    Contact Email: •••••@•••••

    Contact

  • Centrum Badan Klinicznych Pi-house Sp. Z O. O.

    RECRUITING

    Gdansk, Pomeranian Voivodeship, 80-546, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cityclinic Przychodnia lekarsko psychologiczna Matusiak sp.p

    RECRUITING

    Wroclaw, Lower Silesian Voivodeship, 50-566, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Complejo Hospitalario Universitario de Santiago de Compostela

    RECRUITING

    Santiago de Compostela, A Coruna, 15706, Spain

    Contact

    Contact Email: •••••@•••••

  • Dermatology Hospital of Southern Medical University

    RECRUITING

    Guangzhou, Guangdong, 510091, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dermoklinika-Centrum Medyczne s.c

    RECRUITING

    Lodz, 90-436, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Direct Helpers Medical Center

    RECRUITING

    Hialeah, Florida, 33012, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Exalt Clinical Research

    RECRUITING

    Chula Vista, California, 91910, United States

    Contact

    Contact Email: •••••@•••••

  • Fachklinik Bad Bentheim

    RECRUITING

    Bad Bentheim, Lower Saxony, 48455, Germany

    Contact

    Contact Email: •••••@•••••

  • First OC Dermatology Research Inc.

    RECRUITING

    Fountain Valley, California, 92708, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    NOT_YET_RECRUITING

    Rome, 00168, Italy

    Contact

    Contact Email: •••••@•••••

  • Hangzhou First People's Hospital

    RECRUITING

    Hangzhou, Zhejiang, 310006, China

    Contact

    Contact Email: •••••@•••••

  • Hospital Universitario 12 de Octubre

    NOT_YET_RECRUITING

    Madrid, 28041, Spain

    Contact

    Contact Email: •••••@•••••

  • Hospital de La Santa Creu i Sant Pau - Dermatologia

    NOT_YET_RECRUITING

    Barcelona, 08041, Spain

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital of the University of Occupational and Environmental Health, Japan

    RECRUITING

    Kitakyushu-shi, Fukuoka, 807-8555, Japan

    Contact Email: •••••@•••••

    Contact

  • Huashan Hospital Fudan University

    RECRUITING

    Shanghai, 200040, China

    Contact

    Contact Email: •••••@•••••

  • Hunan Children's Hospital

    RECRUITING

    Changsha, Hunan, 410007, China

    Contact Email: •••••@•••••

    Contact

  • Johann Wolfgang Goethe-Universität Frankfurt am Main

    NOT_YET_RECRUITING

    Frankfurt am Main, Hesse, 60596, Germany

    Contact

    Contact Email: •••••@•••••

  • Luxderm Specjalistyczny Gabinet Dermatologiczny Dorota Krasowska

    RECRUITING

    Lublin, Lublin Voivodeship, 20-573, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact

    Contact Email: •••••@•••••

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mie University Hospital

    RECRUITING

    Tsu, Mie, Mie-ken, 514-8507, Japan

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nagoya City University Hospital

    RECRUITING

    Nagoya, Aichi-ken, 467-8602, Japan

    Contact

    Contact Email: •••••@•••••

  • Nippon Life Hospital

    RECRUITING

    Osaka, Osaka, 550-0006, Japan

    Contact

    Contact Email: •••••@•••••

  • Peking University Third Hospital

    RECRUITING

    Beijing, 100191, China

    Contact Email: •••••@•••••

    Contact

  • Presidio Ospedaliero Gaspare Rodolico

    NOT_YET_RECRUITING

    Catania, Sicily, 95123, Italy

    Contact

    Contact Email: •••••@•••••

  • Teikyo University Hospital

    RECRUITING

    Itabashi-Ku, Tokyo, 173-0003, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Texas Dermatology and Laser Specialists-San Antonio

    RECRUITING

    San Antonio, Texas, 78218-3128, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UT Physicians Dermatology - Bellaire Station

    NOT_YET_RECRUITING

    Bellaire, Texas, 77401, United States

    Contact

    Contact Email: •••••@•••••

  • Uniklinik Koln, Klinik fur Dermatologie und Venerologie

    NOT_YET_RECRUITING

    Cologne, North Rhine-Westphalia, 50937, Germany

    Contact

    Contact Email: •••••@•••••

  • Universita Degli Studi Di Padova

    NOT_YET_RECRUITING

    Padova, 35121, Italy

    Contact

    Contact Email: •••••@•••••

  • Universitaetsmedizin der Johannes - Gutenberg Universitaet Mainz

    NOT_YET_RECRUITING

    Mainz, 55131, Germany

    Contact

    Contact Email: •••••@•••••

  • University Hospital of Muenster

    NOT_YET_RECRUITING

    Münster, North Rhine-Westphalia, 48145, Germany

    Contact

    Contact Email: •••••@•••••

  • Universitätsklinikum Bonn

    NOT_YET_RECRUITING

    Bonn, 53127, Germany

    Contact

    Contact Email: •••••@•••••

  • Uniwersytecki Szpital Kliniczny im. Fryderyka Chopina w Rzeszowie

    RECRUITING

    Rzeszów, Podkarpackie Voivodeship, 35-055, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Wright State Physicians

    RECRUITING

    Fairborn, Ohio, 45324, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••