New CLL strategy: only add extra drug if cancer persists
NCT ID NCT05650723
First seen Mar 07, 2026 · Last updated May 16, 2026 · Updated 10 times
Summary
This study tests a personalized approach for people with chronic lymphocytic leukemia (CLL). Instead of giving everyone three drugs from the start, participants first receive two oral medications (zanubrutinib and venetoclax). Only those who still have detectable cancer cells after 16 cycles get an additional antibody treatment (obinutuzumab). The goal is to achieve undetectable cancer levels while avoiding unnecessary side effects. About 50 adults with CLL will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Weill Cornell Medicine/NewYork-Presberteryian Hospital
New York, New York, 10021, United States
Conditions
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