Promising combo tackles tough brain cancer in small trial

NCT ID NCT05681195

First seen Mar 04, 2026 · Last updated Jun 12, 2026 · Updated 16 times

Summary

This study tests a two-drug combination (zanubrutinib and pemetrexed) followed by a maintenance drug for people whose central nervous system lymphoma has returned or stopped responding to treatment. About 15 adults with this rare brain lymphoma will receive the drugs to see if tumors shrink and how safe the treatment is. The goal is to control the disease, not cure it, as patients will need ongoing medication.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Miami Cancer Institute at Baptist Health, Inc.

    RECRUITING

    Miami, Florida, 33176, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.