New combo aims to cut lifelong treatment for rare blood cancer

NCT ID NCT04463953

First seen Feb 14, 2026 · Last updated May 16, 2026 · Updated 20 times

Summary

This study tested a combination of three drugs (zanubrutinib, ixazomib, and dexamethasone) in 25 people newly diagnosed with Waldenström macroglobulinemia, a rare blood cancer. The treatment was given for up to 24 months and then stopped, aiming to achieve deep remission and reduce the need for lifelong therapy. The goal was to see if this time-limited approach works better than standard treatments.

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Contacts and locations

Locations

  • Institute of Hematology & Blood Diseases Hospital

    Tianjin, Tianjin Municipality, 300020, China

Conditions

Explore the condition pages connected to this study.