New CLL strategy: two-drug combo first, extra drug only if needed
NCT ID NCT05650723
First seen Mar 07, 2026 · Last updated Jun 08, 2026 · Updated 15 times
Summary
This study tests a new approach for people with untreated CLL. Instead of giving three drugs to everyone, patients start with two oral medications (zanubrutinib and venetoclax). Only those who still have signs of cancer after 16 cycles get a third drug (obinutuzumab) to boost response. The goal is to achieve undetectable cancer levels while avoiding unnecessary side effects. About 50 adults with CLL or SLL will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Weill Cornell Medicine/NewYork-Presberteryian Hospital
New York, New York, 10021, United States
Conditions
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