Yoga vs. depression: no meds, just mats

NCT ID NCT06091527

Recruiting now Symptom relief Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether yoga alone can reduce symptoms of mild-to-moderate depression. 180 adults with depression will either take 90-minute yoga classes or attend health education classes twice a week for 12 weeks. Researchers will measure changes in depression and stress levels to see if yoga is an effective standalone treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: yoga practice
What this could lead to: If it works, this could offer a drug-free option for managing mild-to-moderate depression.
What could go wrong: This is a small, early-stage trial. Yoga may not work for everyone, and results may not apply to severe depression or those on medication.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION MILD DEPRESSION MODERATE

Contacts and locations

Locations

Zuckerberg San Francisco General Hospital
RECRUITING

San Francisco, California, 94110, United States

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