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Radioactive implant targets pancreatic tumors from the inside

NCT ID NCT07155850

Recruiting now Disease control Sponsor: BetaGlue Therapeutics SpA Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study tests a new device called YntraDose™ that delivers a single dose of radiation directly into pancreatic tumors that cannot be removed by surgery. Ten participants will receive the implant along with standard chemotherapy. The main goals are to see if the procedure is safe and feasible, and to measure its impact on tumor response and quality of life over three months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Y-90 microspheres (radioactive implant) delivered via YntraDose™ device
What this could lead to
If it works, this could offer a new way to treat inoperable pancreatic cancer by delivering radiation directly into the tumor, potentially improving tumor control and quality of life.
What could go wrong
This is a very early, small study (10 people) focused on safety and feasibility. It may not show clear benefit, and there are risks from the procedure and radiation, including possible damage to nearby organs.

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Conditions

The condition(s) this trial relates to.

pancreatic ductal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOCALLY ADVANCED PANCREATIC DUCTAL ADENOCARCINOMA (PDAC) UNRESECTABLE

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fondazione Policlinico Universitario A. Gemelli, IRCCS

    RECRUITING

    Roma, Italy

  • Guy's & St Thomas' and Kings College Hospitals

    RECRUITING

    London, United Kingdom

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